Fuzzy logic as a decision-making support system for the indication of bariatric surgery based on an index (OBESINDEX) generated by the association between body fat and body mass index

Background: A Fuzzy Obesity Index (OBESINDEX) for use as an alternative in bariatric surgery indication (BSI) is presented. The search for a more accurate method to evaluate obesity and to indicate a better treatment is important in the world health context. BMI (body mass index) is considered the main criteria for obesity treatment and BSI. Nevertheless, the fat excess related to the percentage of Body Fat (%BF) is actually the principal harmful factor in obesity disease that is usually neglected. This paper presents a new fuzzy mechanism for evaluating obesity by associating BMI with %BF that yields a fuzzy obesity index for obesity evaluation and treatment and allows building up a Fuzzy Decision Support System (FDSS) for BSI.

Methods: Seventy-two patients were evaluated for both BMI and %BF. These data are modified and treated as fuzzy sets. Afterwards, the BMI and %BF classes are aggregated yielding a new index (OBESINDEX) for input linguistic variable are considered the BMI and %BF, and as output linguistic variable is employed the OBESINDEX, an obesity classification with entirely new classes of obesity in the fuzzy context as well is used for BSI.

Results: There is a gradual, smooth obesity classification and BSI when using the proposed fuzzy obesity index when compared with other traditional methods for dealing with obesity.

Conclusion: The BMI is not adequate for surgical indication in all the conditions and fuzzy logic becomes an alternative for decision making in bariatric surgery indication based on the OBESINDEX

Dynamical Casimir effect with Robin boundary conditions in a three dimensional open cavity

We consider a massless scalar field in 1+1 dimensions inside a cavity composed by a fixed plate, which imposes on the field a Robin BC, and an oscillating one, which imposes on the field a Dirichlet BC. Assuming that the plate moves for a finite time interval, and considering parametric resonance, we compute the total number of created particles inside the cavity. We generalize our results to the case of two parallel plates in 3+1 dimensions.Comment: This work was presented in the Conference QFEXT09, held at the University of Oklahoma, Norman, OK, USA, September 21-25, 2009, and will appear in the proceedings of this conference. It contains 4 figure

A State-of-the-art Integrated Transportation Simulation Platform

Nowadays, universities and companies have a huge need for simulation and modelling methodologies. In the particular case of traffic and transportation, making physical modifications to the real traffic networks could be highly expensive, dependent on political decisions and could be highly disruptive to the environment. However, while studying a specific domain or problem, analysing a problem through simulation may not be trivial and may need several simulation tools, hence raising interoperability issues. To overcome these problems, we propose an agent-directed transportation simulation platform, through the cloud, by means of services. We intend to use the IEEE standard HLA (High Level Architecture) for simulators interoperability and agents for controlling and coordination. Our motivations are to allow multiresolution analysis of complex domains, to allow experts to collaborate on the analysis of a common problem and to allow co-simulation and synergy of different application domains. This paper will start by presenting some preliminary background concepts to help better understand the scope of this work. After that, the results of a literature review is shown. Finally, the general architecture of a transportation simulation platform is proposed

Densifying the sparse cloud SimSaaS: The need of a synergy among agent-directed simulation, SimSaaS and HLA

Modelling & Simulation (M&S) is broadly used in real scenarios where making physical modifications could be highly expensive. With the so-called Simulation Software-as-a-Service (SimSaaS), researchers could take advantage of the huge amount of resource that cloud computing provides. Even so, studying and analysing a problem through simulation may need several simulation tools, hence raising interoperability issues. Having this in mind, IEEE developed a standard for interoperability among simulators named High Level Architecture (HLA). Moreover, the multi-agent system approach has become recognised as a convenient approach for modelling and simulating complex systems. Despite all the recent works and acceptance of these technologies, there is still a great lack of work regarding synergies among them. This paper shows by means of a literature review this lack of work or, in other words, the sparse Cloud SimSaaS. The literature review and the resulting taxonomy are the main contributions of this paper, as they provide a research agenda illustrating future research opportunities and trends

The Incidence of Reserve Requirements in Brazil: Do Bank Stockholders Share the Burden?

There is consensus in the economic literature that the reserve requirements are a tax levied upon financial intermediation, yet the incidence of the tax remains controversial. In this paper, we test whether changes in reserve requirements in Brazil impact the stock returns of the financial system distinctly from the rest of the economy. We find evidence that Brazilian bank stock returns were affected by changes in reserve requirements on both time deposits and transaction accounts, which implies that the tax burden of required reserves was not fully passed through to banks' borrowers or clients. Stock returns of non-financial firms were also affected by these changes, suggesting that in some cases, reserve requirements on time deposits and transaction accounts served as a non-neutral instrument of monetary or fiscal policy in Brazil.

The incidence of reserve requirements in Brazil: Do bank stockholders share the burden?

There is consensus in the economic literature that reserve requirements are a tax levied upon financial intermediation, yet the incidence of the tax remains controversial. In this paper, we test whether changes in reserve requirements in Brazil impact the stock returns of the Brazilian financial system distinctly from the rest of the economy. We show that Brazilian bank stock returns may have been affected by changes in reserve requirements on both time deposits and transaction accounts, which implies that the tax burden of required reserves has not been fully passed through to banks’ borrowers or clients. Stock returns of non-financial firms may also have been affected by changes in reserve requirements, suggesting that in some cases, reserve requirements on time deposits and transaction accounts served as a non-neutral instrument of monetary or fiscal policy in Brazil.tax incidence, reserve requirements, event studies

Interaction between non-disease causing microorganism and E. coli in catheter-associated urinary tract biofilms

Most biofilms involved in catheter-associated urinary tract infections (CAUTIs) are polymicrobial, with disease causing (e.g. E. coli) and non-disease causing (NDC) microorganisms (Delftia tsuruhstensis, Achromobacter xylosoxidans, Burkholderia fungorum) frequently co-inhabiting the same catheter. Nevertheless, there is a lack of knowledge about the role that NDC microorganisms have on biofilm formation by E. coli. This information is essential for a better understanding of CAUTIs etiology. As such, single- and dual-species biofilms were formed in 96-well microtiter plates, using artificial urine medium (AUM). Biofilm quantification was evaluated by crystal violet staining, CFU counts and DAPI counts at 24h, 48h, 96h and 192h. In single-species biofilms, results showed that all species were able to form biofilms (Log 5.84-7.25 CFUs.cm2 at 192h). Concerning dual species biofilms, E. coli appears to have a negative impact on the ability of the NDC species to form biofilms, but, NDC species do not seem to influence E. coli when the two species start forming the biofilm simultaneously and at the same concentration. In fact, the growth rate of E. coli (0.4564 h-1) in AUM is higher than the growth rates of NDC microorganisms (0.0458 h-1–0.131 h-1). Additionally, in dual-species biofilms with an E. coli pre-formed biofilm, the E. coli seems to prevail, even in conditions with a low initial inoculum concentration (102 CFUs.ml-1 vs. 108 CFUs.ml-1 for NDC microorganisms). In conclusion, E. coli has a greater ability to form biofilm in conditions mimicking the CAUTIs, which helps explain why E. coli is the most prevalent agent in CAUTIs

Impact of polymicrobial biofilms in catheter-associated urinary tract infections

Recent reports have demonstrated that most biofilms involved in catheter-associated urinary tract infections are polymicrobial communities, with pathogenic microorganisms (e.g. Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae) and uncommon microorganisms (e.g. Delftia tsuruhatensis, Achromobacter xylosoxidans) frequently co-inhabiting the same urinary catheter. However, little is known about the interactions that occur between different microorganisms and how they impact biofilm formation and infection outcome. This lack of knowledge affects CAUTIs management as uncommon bacteria action can, for instance, influence the rate at which pathogens adhere and grow, as well as affect the overall biofilm resistance to antibiotics. Another relevant aspect is the understanding of factors that drive a single pathogenic bacterium to become prevalent in a polymicrobial community and subsequently cause infection. In this review, a general overview about the IMDs-associated biofilm infections is provided, with an emphasis on the pathophysiology and the microbiome composition of CAUTIs. Based on the available literature, it is clear that more research about the microbiome interaction, mechanisms of biofilm formation and of antimicrobial tolerance of the polymicrobial consortium are required to better understand and treat these infections.This work was financially supported by: Project POCI-010145-FEDER-006939 – Laboratory for Process Engineering, Environment, Biotechnology and Energy – LEPABE funded by FEDER funds through COMPETE2020 – Programa Operacional Competitividade e Internacionalização (POCI) – and by national funds through FCT – Fundacao para a Ci^encia e a Tecnologia; Project “DNAmimics” [PIC/IC/82815/2007]; PhD fellowships [SFRH/BD/82663/2011].info:eu-repo/semantics/publishedVersio